CD20 antibody (PE)
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- Target See all CD20 (MS4A1) Antibodies
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD20 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
- Purpose
- Mouse anti-Human CD20 Antibody [PE Conjugated]
- Specificity
- Predominantly cell surface with some cytoplasmic
- Purification
- The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.
- Immunogen
- The lymphoblastoid cell line Daudi was used as the immunogen for this CD20 antibody.
- Top Product
- Discover our top product MS4A1 Primary Antibody
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- Application Notes
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Flow Cytometry: 5 µL per test per one million cells in 0.1 mL (or 5 µL per 100 µL of whole blood)
Immunofluorescence: 1:50-1:100 - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- 2-8°C. The conjugate is light-sensitive, protect from light.
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- Target
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
- Alternative Name
- B-lymphocyte antigen CD20 (MS4A1 Products)
- Synonyms
- B1 antibody, Bp35 antibody, CD20 antibody, CVID5 antibody, LEU-16 antibody, MS4A2 antibody, S7 antibody, AA960661 antibody, Cd20 antibody, Ly-44 antibody, Ms4a2 antibody, MS4A1 antibody, bp35 antibody, cd20 antibody, ms4a2 antibody, leu-16 antibody, ms4a4c antibody, cd20-like antibody, membrane spanning 4-domains A1 antibody, membrane-spanning 4-domains, subfamily A, member 1 antibody, B-lymphocyte antigen CD20 antibody, MS4A1 antibody, Ms4a1 antibody, ms4a1 antibody, LOC101694281 antibody
- Background
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Target Description: This antibody recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V, Code CD20.12). The antibody recognizes the extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.
Gene Symbol: MS4A1///CD20
- Gene ID
- 931
- UniProt
- P11836
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