CD46 antibody
-
- Target See all CD46 Antibodies
- CD46
-
Reactivity
- Human, Baboon
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This CD46 antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Purpose
- Mouse anti-Human/Baboon CD46 Antibody [Sodium Azide Free]
- Specificity
- Cell surface
- Purification
- Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
- Immunogen
- Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
- Top Product
- Discover our top product CD46 Primary Antibody
-
-
- Application Notes
-
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL - Restrictions
- For Research Use only
-
- Buffer
- In 1X PBS, BSA free, sodium azide free
- Preservative
- Azide free
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
- Target
- CD46
- Alternative Name
- Membrane cofactor protein (CD46 Products)
- Synonyms
- AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
- Background
-
Target Description: Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.
Gene Symbol: CD46///MCP///MIC10
- Gene ID
- 4179
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
-