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PSME3 antibody (C-Term)

PSME3 Reactivity: Human, Rat, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN629645
  • Target See all PSME3 Antibodies
    PSME3
    Binding Specificity
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 46
    • 21
    • 16
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 42
    • 7
    Rabbit
    Clonality
    • 44
    • 5
    Polyclonal
    Conjugate
    • 31
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSME3 antibody is un-conjugated
    Application
    • 35
    • 18
    • 15
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    PSME3 antibody was raised against the C terminal of PSME3
    Purification
    Purified
    Immunogen
    PSME3 antibody was raised using the C terminal of PSME3 corresponding to a region with amino acids TVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY
    Top Product
    Discover our top product PSME3 Primary Antibody
  • Application Notes
    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    PSME3 Blocking Peptide, catalog no. 33R-9372, is also available for use as a blocking control in assays to test for specificity of this PSME3 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PSME3 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    PSME3
    Alternative Name
    PSME3 (PSME3 Products)
    Synonyms
    AA410043 antibody, AU020960 antibody, Ki antibody, PA28gamma antibody, REGgamma antibody, pa28g antibody, Ab2-371 antibody, PA28-gamma antibody, PA28G antibody, REG-GAMMA antibody, psme3b antibody, proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) antibody, proteasome activator subunit 3 antibody, proteasome activator subunit 3 S homeolog antibody, Psme3 antibody, PSME3 antibody, psme3.S antibody
    Background
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. PSME3 is the gamma subunit of the 11S regulator.
    Molecular Weight
    29 kDa (MW of target protein)
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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