RAD23A antibody

Catalog No. ABIN629607

Product Details anti-RAD23A Antibody

Target: RAD23A (RAD23 Homolog A (RAD23A))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD23A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Purified

Immunogen: RAD23 A antibody was raised using a synthetic peptide corresponding to a region with amino acids VPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNN

Application Details

Application Notes: WB: 2.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RAD23A Blocking Peptide, catalog no. 33R-9737, is also available for use as a blocking control in assays to test for specificity of this RAD23A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RAD20 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for RAD23A

Target: RAD23A (RAD23 Homolog A (RAD23A))

Alternative Name: RAD23A (RAD23A Products)

Synonyms: rad23a antibody, wu:fe11h06 antibody, zgc:92001 antibody, RAD23A antibody, HHR23A antibody, HR23A antibody, 2310040P19Rik antibody, AL024030 antibody, mHR23A antibody, RAD23 homolog A, nucleotide excision repair protein a antibody, RAD23 homolog A, nucleotide excision repair protein antibody, rad23aa antibody, RAD23A antibody, Rad23a antibody

Background: RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Molecular Weight: 40 kDa (MW of target protein)

Pathways: DNA Damage Repair