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CSE1L antibody (C-Term)

CSE1L Reactivity: Human, Mouse Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6295024
  • Target See all CSE1L products
    CSE1L (Chromosome Segregation 1-Like (CSE1L))
    Binding Specificity
    AA 55-84, C-Term
    Reactivity
    • 9
    • 9
    • 7
    Human, Mouse
    Host
    • 9
    Rabbit
    Clonality
    • 7
    • 2
    Polyclonal
    Conjugate
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSE1L antibody is un-conjugated
    Application
    Please inquire
    Purpose
    Rabbit Anti-Cellular Apoptosis Susceptibility (C-term) Antibody
    Immunogen
    This Cellular Apoptosis Susceptibility antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the C-terminal region of human Cellular Apoptosis Susceptibility.
  • Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    2-8°C (short-term), -20°C (long-term)
  • Target
    CSE1L (Chromosome Segregation 1-Like (CSE1L))
    Alternative Name
    Cellular Apoptosis Susceptibility (CSE1L Products)
    Synonyms
    2610100P18Rik antibody, AA407533 antibody, Capts antibody, Cas antibody, Xpo2 antibody, cas antibody, chromosome segregation 1-like (S. cerevisiae) antibody, CSE1 chromosome segregation 1-like (yeast) antibody, Cse1l antibody, cse1l antibody
    Background

    Target Description: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.

    Gene Symbol: CSE1L

    Gene ID
    1434
    UniProt
    P55060
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