CSE1L antibody (C-Term)
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- Target See all CSE1L products
- CSE1L (Chromosome Segregation 1-Like (CSE1L))
- Binding Specificity
- AA 55-84, C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CSE1L antibody is un-conjugated
- Application
- Please inquire
- Purpose
- Rabbit Anti-Cellular Apoptosis Susceptibility (C-term) Antibody
- Immunogen
- This Cellular Apoptosis Susceptibility antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the C-terminal region of human Cellular Apoptosis Susceptibility.
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- Restrictions
- For Research Use only
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- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- CSE1L (Chromosome Segregation 1-Like (CSE1L))
- Alternative Name
- Cellular Apoptosis Susceptibility (CSE1L Products)
- Synonyms
- 2610100P18Rik antibody, AA407533 antibody, Capts antibody, Cas antibody, Xpo2 antibody, cas antibody, chromosome segregation 1-like (S. cerevisiae) antibody, CSE1 chromosome segregation 1-like (yeast) antibody, Cse1l antibody, cse1l antibody
- Background
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Target Description: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.
Gene Symbol: CSE1L
- Gene ID
- 1434
- UniProt
- P55060
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