EARS2 antibody

Catalog No. ABIN6293105

Product Details anti-EARS2 Antibody

Target: EARS2 (Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EARS2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human EARS2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for EARS2

Target: EARS2 (Glutamyl-tRNA Synthetase 2 Mitochondrial (EARS2))

Alternative Name: EARS2 (EARS2 Products)

Background: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.

Molecular Weight: 58.689 kDa

Gene ID: 124454

UniProt: Q5JPH6