NLRP11 antibody

Catalog No. ABIN6292815

Product Details anti-NLRP11 Antibody

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP11 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human NLRP11

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for NLRP11

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Alternative Name: NLRP11 (NLRP11 Products)

Synonyms: CLR19.6 antibody, NALP11 antibody, NOD17 antibody, PAN10 antibody, PYPAF6 antibody, PYPAF7 antibody, NLR family pyrin domain containing 11 antibody, NLRP11 antibody

Background: This gene is a member of the the NOD-like receptor protein (NLRP) gene family and encodes a protein with an N-terminal pyrin death (PYD) domain and nucleoside triphosphate hydrolase (NACHT) domain and a C-terminal leucine-rich repeats (LRR) region. This gene has been shown to regulate caspases in the proinflammatory signal transduction pathway and, based on studies of other members of the NLRP gene family with similar domain structure, is predicted to form part of the multiprotein inflammasome complex. Alternative splicing produces multiple transcript variants encoding distince isoforms.

Molecular Weight: 117.779 kDa

Gene ID: 204801

UniProt: P59045

Pathways: Inflammasome