RGD1564237 antibody, GPIHBP1 antibody, GPI-HBP1 antibody, 1110002J19Rik antibody, glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 antibody, GPI-anchored HDL-binding protein 1 antibody, Gpihbp1 antibody, GPIHBP1 antibody
Background
This gene encodes a capillary endothelial cell protein that facilitates the lipolytic processing of triglyceride-rich lipoproteins. The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family. This protein plays a major role in transporting lipoprotein lipase (LPL) from the subendothelial spaces to the capillary lumen. Mutations in this gene are the cause of hyperlipoproteinemia, type 1D. Alternate splicing results in multiple transcript variants.