TICAM1 antibody
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- Target See all TICAM1 Antibodies
- TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TICAM1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human TICAM1
- Isotype
- IgG
- Top Product
- Discover our top product TICAM1 Primary Antibody
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- Application Notes
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - Comment
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Ubiquitously expressed but with higher levels in liver
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))
- Alternative Name
- TICAM1 (TICAM1 Products)
- Synonyms
- IIAE6 antibody, MyD88-3 antibody, PRVTIRB antibody, TICAM-1 antibody, TRIF antibody, AW046014 antibody, AW547018 antibody, trif antibody, toll like receptor adaptor molecule 1 antibody, toll-like receptor adaptor molecule 1 antibody, TICAM1 antibody, Ticam1 antibody, ticam1 antibody
- Background
- This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.
- Molecular Weight
- 76.422 kDa
- Gene ID
- 148022
- UniProt
- Q8IUC6
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
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