PHLDA2 antibody
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- Target See all PHLDA2 Antibodies
- PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PHLDA2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human PHLDA2
- Isotype
- IgG
- Top Product
- Discover our top product PHLDA2 Primary Antibody
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- Application Notes
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WB 1:500 - 1:2000
IHC 1:50 - 1:200 - Comment
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Expressed in placenta and adult prostate gland, In placenta, it is present in all cells of the villous cytotrophoblast, The protein is absent in cells from hydatidiform moles, Hydatidiform mole is a gestation characterized by abnormal development of both fetus and trophoblast, The majority of hydatidiform moles are associated with an excess of paternal to maternal genomes and are likely to result from the abnormal expression of imprinted genes (at protein level), Expressed at low levels in adult liver and lung, and fetal liver, Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))
- Alternative Name
- PHLDA2 (PHLDA2 Products)
- Synonyms
- PHLDA2 antibody, ipl antibody, phlda2 antibody, BRW1C antibody, BWR1C antibody, HLDA2 antibody, IPL antibody, TSSC3 antibody, Ipl antibody, Tssc3 antibody, zgc:110459 antibody, pleckstrin homology like domain family A member 2 antibody, Pleckstrin homology-like domain family A member 2 antibody, pleckstrin homology like domain, family A, member 2 antibody, pleckstrin homology-like domain, family A, member 2 antibody, pleckstrin homology-like domain, family A, member 2 L homeolog antibody, PHLDA2 antibody, phla2 antibody, Phlda2 antibody, phlda2.L antibody, phlda2 antibody
- Background
- This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.
- Molecular Weight
- 17.092 kDa
- Gene ID
- 7262
- UniProt
- Q53GA4
- Pathways
- Regulation of Carbohydrate Metabolic Process
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