ARAP2 antibody

Catalog No. ABIN6291255

This anti-ARAP2 antibody is a Rabbit Polyclonal antibody detecting ARAP2 in WB. Suitable for Human and Mouse.

Quick Overview for ARAP2 antibody (ABIN6291255)

Target: ARAP2 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 2 (ARAP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARAP2 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human ARAP2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Detected in brain, thymus, lymph node, thyroid, spinal cord, trachea, heart, skeletal muscle, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for ARAP2

Target: ARAP2 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 2 (ARAP2))

Alternative Name: ARAP2

Background: The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.

Molecular Weight: 193.452 kDa

Gene ID: 116984

UniProt: Q8WZ64