PCDHB16 antibody

Catalog No. ABIN6291191

Product Details anti-PCDHB16 Antibody

Target: PCDHB16 (Protocadherin beta 16 (PCDHB16))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB16 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human PCDHB16

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for PCDHB16

Target: PCDHB16 (Protocadherin beta 16 (PCDHB16))

Alternative Name: PCDHB16 (PCDHB16 Products)

Synonyms: ME1 antibody, PCDH-BETA16 antibody, PCDH3X antibody, PCDHB8a antibody, Pcdhb8 antibody, PcdhbP antibody, PCDHB16 antibody, Pcdhb8a antibody, PCDHB8 antibody, protocadherin beta 16 antibody, protocadherin beta-16 antibody, protocadherin beta 6 antibody, PCDHB16 antibody, Pcdhb16 antibody, LOC100848138 antibody, LOC100349989 antibody, PCDHB6 antibody

Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Molecular Weight: 84.983 kDa

Gene ID: 57717

UniProt: Q9NRJ7