KIF7 antibody
-
- Target See all KIF7 Antibodies
- KIF7 (Kinesin Family Member 7 (KIF7))
-
Reactivity
- Human, Rat, Mouse
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This KIF7 antibody is un-conjugated
-
Application
- Immunofluorescence (IF)
- Purpose
- Kif 7 is a protein encoded by the KIF7 gene which is approximately 150,5 kDa. Kif 7 is localised to the cilium tip. It is involved in signalling by hedgehog and GPCR. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of a ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Kif 7 is expressed in embryonic stem cells and Jurkat T-cells. Mutations in the KIF7 gene may result in Bardet-Biedl syndrome. STJ96965 was developed from clone 3F8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous Kif 7 proteins.
- Specificity
- The antibody detects endogenous Kif 7 proteins.
- Characteristics
- Mouse monoclonal to Kif 7.
- Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Immunogen
- Synthetic Peptide
- Clone
- 3F8
- Isotype
- IgG1
- Top Product
- Discover our top product KIF7 Primary Antibody
-
-
- Application Notes
- IHC 1:200
- Comment
-
Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
- Target
- KIF7 (Kinesin Family Member 7 (KIF7))
- Alternative Name
- Kif 7 (KIF7 Products)
- Synonyms
- KIF7 antibody, DDBDRAFT_0204609 antibody, DDBDRAFT_0206583 antibody, DDB_0204609 antibody, DDB_0206583 antibody, ACLS antibody, HLS2 antibody, JBTS12 antibody, UNQ340 antibody, cos2 antibody, costal2 antibody, kinesin family member 7 antibody, KIF7 antibody, kif7 antibody, Kif7 antibody
- Gene ID
- 374654
- UniProt
- Q2M1P5
- Pathways
- Hedgehog Signaling
-