VGF antibody (Internal Region)
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- Target See all VGF Antibodies
- VGF (VGF Nerve Growth Factor Inducible (VGF))
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Binding Specificity
- AA 441-490, Internal Region
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VGF antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- VGF is a protein encoded by the VGF gene which is approximately 67,2 kDa. VGF is secreted and is involved in growth factor activity and neuropeptide hormone activity. VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. It may be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system. VGF is expressed in the central and peripheral nervous systems, it is synthesized exclusively in neuronal and neuroendocrine cells. Mutations in the VGF gene may result in pulmonary large cell Neuroendocrine Carcinoma and Pheochromocytoma. STJ96661 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of VGF protein.
- Specificity
- VGF Polyclonal Antibody detects endogenous levels of VGF protein.
- Characteristics
- Rabbit polyclonal to VGF.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human VGF.
- Isotype
- IgG
- Top Product
- Discover our top product VGF Primary Antibody
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- Application Notes
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WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000 - Comment
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Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- VGF (VGF Nerve Growth Factor Inducible (VGF))
- Alternative Name
- VGF (VGF Products)
- Synonyms
- VGF antibody, Gm1052 antibody, VGF nerve growth factor inducible antibody, VGF antibody, Vgf antibody
- Molecular Weight
- 67 kDa
- Gene ID
- 7425
- UniProt
- O15240
- Pathways
- Hormone Transport, Carbohydrate Homeostasis
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