SHC3 antibody (Internal Region)

Catalog No. ABIN6282663

Product Details anti-SHC3 Antibody

Target: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Binding Specificity: AA 260-340, Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHC3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal to N-Shc.

Specificity: N-Shc Polyclonal Antibody detects endogenous levels of N-Shc protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human N-Shc

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300
ELISA 1:10000

Comment:

Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for SHC3

Target: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Alternative Name: N-Shc (SHC3 Products)

Synonyms: N-Shc antibody, NSHC antibody, RAI antibody, SHCC antibody, ShcC antibody, Rai antibody, SHC adaptor protein 3 antibody, src homology 2 domain-containing transforming protein C3 antibody, SHC3 antibody, Shc3 antibody

Molecular Weight: 48 kDa

Gene ID: 53358

UniProt: Q92529

Pathways: RTK Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway