TRIM63 antibody (N-Term)
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- Target See all TRIM63 Antibodies
- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRIM63 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- TRIM63 Antibody detects endogenous levels of total TRIM63.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TRIM63, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TRIM63 Primary Antibody
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anti-Tripartite Motif Containing 63 (TRIM63) (AA 1-353) antibody
TRIM63 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 293-304) antibodyTRIM63 Reactivity: Human ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 7B8E1 unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 254-352) antibodyTRIM63 Reactivity: Human WB, ELISA, IF, RNAi Host: Mouse Monoclonal 6G6 unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 251-353) antibodyTRIM63 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 254-352) antibodyTRIM63 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (N-Term) antibodyVerified TRIM63 Reactivity: Human ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 251-300) antibodyTRIM63 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig, Bat, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 63 (TRIM63) (AA 1-353) antibodyTRIM63 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- TRIM63 (Tripartite Motif Containing 63 (TRIM63))
- Alternative Name
- TRIM63 (TRIM63 Products)
- Background
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Description: E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
Gene: TRIM63
- Molecular Weight
- 40kDa
- Gene ID
- 84676
- UniProt
- Q969Q1
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