HCRTR2 antibody (N-Term)

Catalog No. ABIN6266228

Product Details anti-HCRTR2 Antibody

Target: HCRTR2 (Hypocretin (Orexin) Receptor 2 (HCRTR2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCRTR2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: HCRTR2 Antibody detects endogenous levels of total HCRTR2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HCRTR2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for HCRTR2

Target: HCRTR2 (Hypocretin (Orexin) Receptor 2 (HCRTR2))

Alternative Name: HCRTR2 (HCRTR2 Products)

Synonyms: LOC100229747 antibody, LOC443181 antibody, hcrtr antibody, OX2R antibody, mOX2aR antibody, mOX2bR antibody, mOXR2 antibody, hypocretin receptor 2 antibody, hypocretin (orexin) receptor 2 antibody, HCRTR2 antibody, hcrtr2 antibody, Hcrtr2 antibody

Background:

Description: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca2+ levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).

Gene: HCRTR2

Molecular Weight: 51kDa

Gene ID: 3062

UniProt: O43614

Pathways: Feeding Behaviour