GRK1 antibody (N-Term)

Catalog No. ABIN6266219

Product Details anti-GRK1 Antibody

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: GRK1 Antibody detects endogenous levels of total GRK1.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human GRK1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GRK1

Target: GRK1 (G Protein-Coupled Receptor Kinase 1 (GRK1))

Alternative Name: GRK1 (GRK1 Products)

Synonyms: GPRK1 antibody, RHOK antibody, RK antibody, Gprk1 antibody, Rhok antibody, Rk antibody, CG40129 antibody, CT4320 antibody, Dmel\\CG40129 antibody, Gprk-1 antibody, Rok antibody, gprk1 antibody, grk1 antibody, zgc:112194 antibody, G protein-coupled receptor kinase 1 antibody, G protein-coupled receptor kinase 1 a antibody, G protein-coupled receptor kinase 1 b antibody, GRK1 antibody, Grk1 antibody, Gprk1 antibody, grk1a antibody, grk1b antibody

Background:

Description: Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.

Gene: GRK1

Molecular Weight: 63.5kDa

Gene ID: 6011

UniProt: Q15835

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction