ZKSCAN3 antibody (Internal Region)

Catalog No. ABIN6266108

Product Details anti-ZKSCAN3 Antibody

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZKSCAN3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ZKSCAN3 Antibody detects endogenous levels of total ZKSCAN3.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZKSCAN3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ZKSCAN3

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Alternative Name: ZKSCAN3 (ZKSCAN3 Products)

Synonyms: ZKSCAN3 antibody, ZNF306 antibody, ZF47 antibody, ZFP306 antibody, ZNF309 antibody, ZSCAN13 antibody, ZSCAN35 antibody, Zfp47 antibody, dJ874C20.1 antibody, dJ874C20.1. antibody, zfp-47 antibody, 2810435N07Rik antibody, AA408594 antibody, AI132359 antibody, Skz1 antibody, Zf47 antibody, Zfp-47 antibody, Zfp306 antibody, Zfp307 antibody, mszf35 antibody, zinc finger with KRAB and SCAN domains 3 antibody, ZKSCAN3 antibody, Zkscan3 antibody

Background:

Description: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.

Gene: ZKSCAN3

Molecular Weight: 61 kDa

Gene ID: 80317

UniProt: Q9BRR0