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YTHDF1 antibody (N-Term)

YTHDF1 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6266080
  • Target See all YTHDF1 products
    YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
    Binding Specificity
    • 4
    • 3
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 20
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 20
    Rabbit
    Clonality
    • 19
    • 1
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This YTHDF1 antibody is un-conjugated
    Application
    • 11
    • 7
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    YTHDF1 Antibody detects endogenous levels of total YTHDF1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human YTHDF1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))
    Alternative Name
    YTHDF1 (YTHDF1 Products)
    Synonyms
    fb49c02 antibody, zgc:55657 antibody, wu:fb49c02 antibody, wu:fi19h06 antibody, wu:fj87f09 antibody, wu:fp06c11 antibody, MGC75606 antibody, MGC68505 antibody, 2210410K23Rik antibody, 8030473O16 antibody, C20orf21 antibody, YTH N(6)-methyladenosine RNA binding protein 1 antibody, YTH N(6)-methyladenosine RNA binding protein 1 L homeolog antibody, YTH N6-methyladenosine RNA binding protein 1 antibody, YTH domain family 1 antibody, ythdf1 antibody, ythdf1.L antibody, YTHDF1 antibody, Ythdf1 antibody
    Background

    Description: Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440).

    Gene: YTHDF1

    Molecular Weight
    61kDa
    Gene ID
    54915
    UniProt
    Q9BYJ9
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