Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

XPO4 antibody (N-Term)

XPO4 Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6266065
  • Target See all XPO4 Antibodies
    XPO4 (Exportin 4 (XPO4))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 11
    • 10
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 10
    • 1
    Rabbit
    Clonality
    • 10
    • 1
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XPO4 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Specificity
    XPO4 Antibody detects endogenous levels of total XPO4.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human XPO4, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    XPO4 (Exportin 4 (XPO4))
    Alternative Name
    XPO4 (XPO4 Products)
    Synonyms
    XPO4 antibody, MGC157258 antibody, DDBDRAFT_0215248 antibody, DDBDRAFT_0237580 antibody, DDB_0215248 antibody, DDB_0237580 antibody, exp4 antibody, B430309A01Rik antibody, mKIAA1721 antibody, fc26b07 antibody, wu:fc26b07 antibody, wu:fi43b10 antibody, zgc:55678 antibody, exportin 4 antibody, exportin 4 L homeolog antibody, XPO4 antibody, xpo4 antibody, Xpo4 antibody, xpo4.L antibody
    Background

    Description: Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

    Gene: XPO4

    Molecular Weight
    127 kDa
    Gene ID
    64328
    UniProt
    Q9C0E2
You are here:
Support