WASF1 antibody (Internal Region)

Catalog No. ABIN6266012

Product Details anti-WASF1 Antibody

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WASF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: WAVE1 Antibody detects endogenous levels of total WAVE1.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WAVE1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for WASF1

Target: WASF1 (WAS Protein Family, Member 1 (WASF1))

Alternative Name: WASF1 (WASF1 Products)

Synonyms: scar1 antibody, wave1 antibody, ATRANGAP2 antibody, ATSCAR1 antibody, SCAR1 antibody, T14G11.27 antibody, T14G11_27 antibody, WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY VERPROLIN HOMOLOGOUS PROTEIN 1 antibody, wave antibody, WAVE antibody, WAVE1 antibody, AI195380 antibody, AI838537 antibody, Scar antibody, WAVE-1 antibody, WAS protein family member 1 S homeolog antibody, SCAR family protein antibody, WAS protein family member 1 antibody, WAS protein family, member 1 antibody, wasf1.S antibody, AT2G34150 antibody, wasf1 antibody, WASF1 antibody, Wasf1 antibody

Background:

Description: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).

Gene: WASF1

Molecular Weight: 70kDa

Gene ID: 8936

UniProt: Q92558

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization