WARS antibody (Internal Region)

Catalog No. ABIN6266008

Product Details anti-WARS Antibody

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: WARS Antibody detects endogenous levels of total WARS.

Predicted Reactivity: Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WARS, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for WARS

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Alternative Name: WARS (WARS Products)

Synonyms: GAMMA-2 antibody, IFI53 antibody, IFP53 antibody, zgc:73274 antibody, wars antibody, MGC53671 antibody, WARS antibody, TrpRS antibody, WRS antibody, 85D-WRS antibody, CG9735 antibody, Dmel\\CG9735 antibody, WRS-85D antibody, l(3)03559 antibody, l(3)03560 antibody, l(3)3559 antibody, gamma-2 antibody, ifi53 antibody, ifp53 antibody, GB14934 antibody, ECK3371 antibody, JW3347 antibody, tryptophanyl-tRNA synthetase antibody, tryptophanyl-tRNA synthetase S homeolog antibody, Tryptophanyl-tRNA synthetase antibody, tryptophanyl-tRNA synthetase L homeolog antibody, tryptophan--tRNA ligase, cytoplasmic antibody, WARS antibody, wars antibody, wars.S antibody, Wars antibody, TrpRS antibody, wars.L antibody, LOC727582 antibody, trpS antibody, trpS2 antibody

Background:

Description: Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.

Gene: WARS

Molecular Weight: 25 kDa

Gene ID: 7453

UniProt: P23381