USP6 antibody

Catalog No. ABIN6265934

Product Details anti-USP6 Antibody

Target: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP6 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: USP6 Antibody detects endogenous levels of total USP6

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human USP6

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for USP6

Target: USP6 (Ubiquitin Specific Peptidase 6 (USP6))

Alternative Name: USP6 (USP6 Products)

Synonyms: HRP1 antibody, TRE2 antibody, TRE17 antibody, Tre-2 antibody, USP6-short antibody, ubiquitin specific peptidase 6 antibody, ubiquitin carboxyl-terminal hydrolase 6 antibody, Ubiquitin carboxyl-terminal hydrolase 6, putative antibody, USP6 antibody, CNG04540 antibody, ANI_1_2152104 antibody, AOR_1_208094 antibody, MCYG_00569 antibody, CC1G_15273 antibody, MGYG_01395 antibody, CGB_G0160W antibody, LOC100282385 antibody

Background:

Description: Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Gene: USP6

Molecular Weight: 159 kDa

Gene ID: 9098

UniProt: P35125