Ubinuclein 1 antibody (Internal Region)

Catalog No. ABIN6265859

Product Details anti-Ubinuclein 1 Antibody

Target: Ubinuclein 1 (UBN1)

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubinuclein 1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: Ubinuclein Antibody detects endogenous levels of total Ubinuclein.

Predicted Reactivity: Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Ubinuclein, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Ubinuclein 1

Target: Ubinuclein 1 (UBN1)

Alternative Name: UBN1 (UBN1 Products)

Synonyms: ubinuclein-1 antibody, ubn1 antibody, VT antibody, VT4 antibody, 1110029L11Rik antibody, 2610108L02Rik antibody, AA673476 antibody, AW124741 antibody, ubinuclein 1 antibody, UBN1 antibody, ubn1 antibody, Ubn1 antibody

Background:

Description: Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly.

Gene: UBN1

Molecular Weight: 121 kDa

Gene ID: 29855

UniProt: Q9NPG3