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TTL antibody

TTL Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265786
  • Target See all TTL Antibodies
    TTL (Tubulin tyrosine Ligase (TTL))
    Reactivity
    • 28
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 26
    • 3
    Rabbit
    Clonality
    • 26
    • 3
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    This TTL antibody is un-conjugated
    Application
    • 21
    • 21
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    TTL antibody detects endogenous levels of TTL.
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TTL.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    TTL (Tubulin tyrosine Ligase (TTL))
    Alternative Name
    TTL (TTL Products)
    Synonyms
    2410003M22Rik antibody, 2700049H19Rik antibody, AI848570 antibody, wu:fb93a09 antibody, zgc:153332 antibody, tubulin tyrosine ligase antibody, Ttl antibody, TTL antibody, ttl antibody
    Background

    Description: Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Generates long side-chains. Generates polyglutamylation of CGAS, leading to impair the DNA-binding activity of CGAS.

    Gene: TTLL6

    Molecular Weight
    43-45 kDa
    Gene ID
    284076
    UniProt
    Q8N841
    Pathways
    Regulation of Cell Size
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