TTL antibody
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- Target See all TTL Antibodies
- TTL (Tubulin tyrosine Ligase (TTL))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TTL antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- TTL antibody detects endogenous levels of TTL.
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TTL.
- Isotype
- IgG
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- TTL (Tubulin tyrosine Ligase (TTL))
- Alternative Name
- TTL (TTL Products)
- Synonyms
- 2410003M22Rik antibody, 2700049H19Rik antibody, AI848570 antibody, wu:fb93a09 antibody, zgc:153332 antibody, tubulin tyrosine ligase antibody, Ttl antibody, TTL antibody, ttl antibody
- Background
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Description: Polyglutamylase which preferentially modifies alpha-tubulin. Mediates tubulin polyglutamylation in cilia. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Generates long side-chains. Generates polyglutamylation of CGAS, leading to impair the DNA-binding activity of CGAS.
Gene: TTLL6
- Molecular Weight
- 43-45 kDa
- Gene ID
- 284076
- UniProt
- Q8N841
- Pathways
- Regulation of Cell Size
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