FOXE1 antibody (N-Term)

Catalog No. ABIN6265782

Product Details anti-FOXE1 Antibody

Target: FOXE1 (Forkhead Box E1 (Thyroid Transcription Factor 2) (FOXE1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXE1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: TTF2 Antibody detects endogenous levels of total TTF2.

Predicted Reactivity: Bovine

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TTF2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for FOXE1

Target: FOXE1 (Forkhead Box E1 (Thyroid Transcription Factor 2) (FOXE1))

Alternative Name: FOXE1 (FOXE1 Products)

Synonyms: FKHL15 antibody, FOXE2 antibody, HFKH4 antibody, HFKL5 antibody, TITF2 antibody, TTF-2 antibody, TTF2 antibody, Titf2 antibody, Ttf-2 antibody, Ci-FoxE antibody, Foxe1 antibody, FoxE5 antibody, ttf2 antibody, foxe2 antibody, hfkh4 antibody, hfkl5 antibody, titf2 antibody, ttf-2 antibody, fkhl15 antibody, foxE1 antibody, foxE antibody, forkhead box E1 antibody, foxE protein antibody, forkhead box E1 L homeolog antibody, FOXE1 antibody, Foxe1 antibody, foxE antibody, foxe1.L antibody, foxe1 antibody, foxE1 antibody

Background:

Description: Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.

Gene: FOXE1

Molecular Weight: 34kDa

Gene ID: 2304

UniProt: O00358