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TSH receptor antibody (Internal Region)

TSHR Reactivity: Human, Mouse WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265772
  • Target See all TSH receptor (TSHR) Antibodies
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Binding Specificity
    • 16
    • 16
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 86
    • 51
    • 36
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Human, Mouse
    Host
    • 74
    • 14
    • 1
    • 1
    Rabbit
    Clonality
    • 75
    • 15
    Polyclonal
    Conjugate
    • 44
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSH receptor antibody is un-conjugated
    Application
    • 44
    • 40
    • 20
    • 17
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    TSHR Antibody detects endogenous levels of total TSHR.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TSHR, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product TSHR Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Alternative Name
    TSHR (TSHR Products)
    Synonyms
    CHNG1 antibody, LGR3 antibody, hTSHR-I antibody, AI481368 antibody, hypothroid antibody, hyt antibody, pet antibody, TSHRA antibody, TSH-R antibody, thyroid stimulating hormone receptor antibody, tshr antibody, TSHR antibody, Tshr antibody
    Background

    Description: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).

    Gene: TSHR

    Molecular Weight
    62-70 kDa
    Gene ID
    7253
    UniProt
    P16473
    Pathways
    Thyroid Hormone Synthesis
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