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TSG101 antibody

TSG101 Reactivity: Human, Monkey WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265767
  • Target See all TSG101 Antibodies
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    Reactivity
    • 70
    • 41
    • 30
    • 11
    • 9
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Monkey
    Host
    • 61
    • 12
    Rabbit
    Clonality
    • 53
    • 20
    Polyclonal
    Conjugate
    • 48
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TSG101 antibody is un-conjugated
    Application
    • 58
    • 29
    • 25
    • 13
    • 11
    • 11
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    TSG101 Antibody detects endogenous levels of total TSG101
    Cross-Reactivity
    Human, Monkey
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TSG101
    Isotype
    IgG
    Top Product
    Discover our top product TSG101 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    Alternative Name
    TSG101 (TSG101 Products)
    Background

    Description: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed:22315426).

    Gene: TSG101

    Molecular Weight
    45 kDa
    Gene ID
    7251
    UniProt
    Q99816
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