TRIM29 antibody (Internal Region)
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- Target See all TRIM29 Antibodies
- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRIM29 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- TRIM29 Antibody detects endogenous levels of total TRIM29.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TRIM29, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product TRIM29 Primary Antibody
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anti-Tripartite Motif Containing 29 (TRIM29) (AA 451-588) antibody
TRIM29 Reactivity: Human WB, ELISA, FACS, ICC Host: Mouse Monoclonal 8C8G5 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (Internal Region) antibodyVerified TRIM29 Reactivity: Human WB, ELISA, IHC, IF, FACS Host: Goat Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 Reactivity: Human ELISA, IHC, Coat, StM Host: Mouse Monoclonal TRIM29-1041 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 Reactivity: Human IHC Host: Mouse Monoclonal MSVA-629M unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 309-588) antibodyTRIM29 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (Internal Region) antibodyTRIM29 Reactivity: Human, Cow, Horse, Macaque, Chimpanzee WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 Reactivity: Human WB, ELISA, Coat Host: Mouse Monoclonal TRIM29-1042 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-588) antibodyTRIM29 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (C-Term) antibodyTRIM29 Reactivity: Human, Mouse, Rat, Cow, Horse, Guinea Pig, Dog, Monkey, Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 253-283) antibodyTRIM29 Reactivity: Human, Mouse, Rat WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
- Alternative Name
- TRIM29 (TRIM29 Products)
- Background
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Description: Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of proinflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of TMEM173/STING in a similar way, leading to its degradation.
Gene: TRIM29
- Molecular Weight
- 66 kDa
- Gene ID
- 23650
- UniProt
- Q14134
- Pathways
- p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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