Tropomyosin antibody (N-Term)

Catalog No. ABIN6265690

Product Details anti-Tropomyosin Antibody

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tropomyosin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: TPM1 Antibody detects endogenous levels of total TPM1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TPM1, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Tropomyosin

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Alternative Name: TPM1 (TPM1 Products)

Synonyms: alpha-fTM antibody, Tm7 antibody, tpm1 antibody, MGC84844 antibody, AA986836 antibody, AI854628 antibody, TM2 antibody, Tm3 antibody, Tmpa antibody, Tpm-1 antibody, alpha-TM antibody, Alpha-tm antibody, Tma2 antibody, Tmsa antibody, TPM1 antibody, fb37a09 antibody, tm antibody, wu:fb37a09 antibody, CH1 antibody, alpha-tm antibody, alpha-tropomyosin antibody, C15orf13 antibody, CMD1Y antibody, CMH3 antibody, HTM-alpha antibody, TMSA antibody, TPMA antibody, Tm1 antibody, zgc:171719 antibody, zgc:55951 antibody, zgc:77009 antibody, tropomyosin 1 (alpha) antibody, tropomyosin antibody, tropomyosin 1 antibody, tropomyosin 1, alpha antibody, alpha-tropomyosin antibody, tropomyosin 1 L homeolog antibody, TPM1 antibody, tm7 antibody, Tpm1 antibody, tpma antibody, tpm1.L antibody, Smp_044010.2 antibody, LOC732984 antibody, tpm1 antibody

Background:

Description: Binds to actin filaments in muscle and non-muscle cells (PubMed:23170982). Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction (PubMed:23170982). Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

Gene: TPM1

Molecular Weight: 33kDa

Gene ID: 7168

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization