TGIF1 antibody (C-Term)

Catalog No. ABIN6265552

Product Details anti-TGIF1 Antibody

Target: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGIF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: TGIF1 Antibody detects endogenous levels of total TGIF1.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TGIF1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TGIF1

Target: TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))

Alternative Name: TGIF1 (TGIF1 Products)

Synonyms: HPE4 antibody, TGIF antibody, AA959811 antibody, AI462167 antibody, Tgif antibody, Tfig antibody, fa06h05 antibody, fb33g11 antibody, zgc:55852 antibody, wu:fa06h05 antibody, wu:fb33g11 antibody, hpe4 antibody, tgif antibody, tgif1 antibody, TGFB induced factor homeobox 1 antibody, TGFB-induced factor homeobox 1 antibody, TGFB induced factor homeobox 1 S homeolog antibody, TGIF1 antibody, Tgif1 antibody, tgif1 antibody, tgif1.S antibody

Background:

Description: Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities.

Gene: TGIF1

Molecular Weight: 45 kDa

Gene ID: 7050

UniProt: Q15583

Pathways: Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation