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TCTN1 antibody (N-Term)

TCTN1 Reactivity: Rat, Human, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265507
  • Target See all TCTN1 Antibodies
    TCTN1 (Tectonic Family Member 1 (TCTN1))
    Binding Specificity
    • 15
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    Rat, Human, Mouse
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TCTN1 antibody is un-conjugated
    Application
    • 18
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificity
    TCTN1 Antibody detects endogenous levels of total TCTN1.
    Predicted Reactivity
    Pig
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TCTN1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    TCTN1 (Tectonic Family Member 1 (TCTN1))
    Alternative Name
    TCTN1 (TCTN1 Products)
    Synonyms
    FLJ21127 antibody, JBTS13 antibody, TECT1 antibody, G730031O11Rik antibody, Tect1 antibody, RGD1566266 antibody, tectonic family member 1 antibody, tectonic family member 1 L homeolog antibody, TCTN1 antibody, tctn1.L antibody, tctn1 antibody, Tctn1 antibody
    Background

    Description: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity).

    Gene: TCTN1

    Molecular Weight
    55-64kDa
    Gene ID
    79600
    UniProt
    Q2MV58
    Pathways
    Tube Formation
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