TBC1D2 antibody (N-Term)

Catalog No. ABIN6265478

Product Details anti-TBC1D2 Antibody

Target: TBC1D2 (TBC1 Domain Family, Member 2 (TBC1D2))

Binding Specificity: N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBC1D2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: TBC1D2 Antibody detects endogenous levels of total TBC1D2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TBC1D2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TBC1D2

Target: TBC1D2 (TBC1 Domain Family, Member 2 (TBC1D2))

Alternative Name: TBC1D2 (TBC1D2 Products)

Synonyms: PARIS-1 antibody, PARIS1 antibody, TBC1D2A antibody, A630005A06Rik antibody, BC022630 antibody, Gm1037 antibody, TBC1 domain family member 2 antibody, TBC1 domain family, member 2 antibody, TBC1D2 antibody, Tbc1d2 antibody

Background:

Description: Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.

Gene: TBC1D2

Molecular Weight: 105 kDa

Gene ID: 55357

UniProt: Q9BYX2