TBXA2R antibody (C-Term)

Catalog No. ABIN6265456

Product Details anti-TBXA2R Antibody

Target: TBXA2R (Thromboxane A2 Receptor (TBXA2R))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXA2R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: TAS2R Antibody detects endogenous levels of total TAS2R.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TAS2R, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TBXA2R

Target: TBXA2R (Thromboxane A2 Receptor (TBXA2R))

Alternative Name: TBXA2R (TBXA2R Products)

Synonyms: tbxa2r antibody, MGC80805 antibody, TBXA2R antibody, BDPLT13 antibody, TXA2-R antibody, TP antibody, thromboxane A2 receptor L homeolog antibody, thromboxane A2 receptor antibody, tbxa2r.L antibody, TBXA2R antibody, tbxa2r antibody, Tbxa2r antibody

Background:

Description: Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.

Gene: TBXA2R

Molecular Weight: 37 kDa

Gene ID: 6915

UniProt: P21731