beta Synuclein antibody (C-Term)
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- Target See all beta Synuclein (SNCB) Antibodies
- beta Synuclein (SNCB) (Synuclein, beta (SNCB))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This beta Synuclein antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Synuclein beta Antibody detects endogenous levels of total Synuclein beta.
- Predicted Reactivity
- Rabbit
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Synuclein beta, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SNCB Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- beta Synuclein (SNCB) (Synuclein, beta (SNCB))
- Alternative Name
- SNCB (SNCB Products)
- Synonyms
- AI838531 antibody, betaSYN antibody, zgc:66343 antibody, sncb antibody, MGC75784 antibody, LOC619281 antibody, SNCB antibody, syub antibody, synuclein beta antibody, synuclein, beta antibody, synuclein beta L homeolog antibody, Beta-synuclein antibody, SNCB antibody, Sncb antibody, sncb antibody, sncb.L antibody, syub antibody
- Background
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Description: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Gene: SNCB
- Molecular Weight
- 14 kDa
- Gene ID
- 6620
- UniProt
- Q16143
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