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SYNGAP1 antibody (C-Term)

SYNGAP1 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265400
  • Target See all SYNGAP1 Antibodies
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    Binding Specificity
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 20
    • 15
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 19
    • 2
    Rabbit
    Clonality
    • 18
    • 3
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYNGAP1 antibody is un-conjugated
    Application
    • 10
    • 7
    • 5
    • 2
    • 2
    Western Blotting (WB), ELISA
    Specificity
    SYNGAP1 Antibody detects endogenous levels of total SYNGAP1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SYNGAP1, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product SYNGAP1 Primary Antibody
  • Application Notes
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
    Alternative Name
    SYNGAP1 (SYNGAP1 Products)
    Synonyms
    SYNGAP1 antibody, Syngap antibody, MRD5 antibody, RASA1 antibody, RASA5 antibody, SYNGAP antibody, Gm1963 antibody, synaptic Ras GTPase activating protein 1 antibody, zinc finger and BTB domain containing 9 antibody, synaptic Ras GTPase activating protein 1 homolog (rat) antibody, SYNGAP1 antibody, ZBTB9 antibody, syngap1 antibody, Syngap1 antibody
    Background

    Description: Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).

    Gene: SYNGAP1

    Molecular Weight
    147 kDa
    Gene ID
    8831
    UniProt
    Q96PV0
    Pathways
    Regulation of long-term Neuronal Synaptic Plasticity
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