STAM2 antibody
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- Target See all STAM2 Antibodies
- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This STAM2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- STAM2 Antibody detects endogenous levels of total STAM2
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human STAM2
- Isotype
- IgG
- Top Product
- Discover our top product STAM2 Primary Antibody
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- Application Notes
- WB 1:1000, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))
- Alternative Name
- STAM2 (STAM2 Products)
- Synonyms
- Hbp antibody, STAM2A antibody, STAM2B antibody, 1200004O12Rik antibody, 5730456G07Rik antibody, BB145015 antibody, stam2 antibody, MGC52950 antibody, zgc:103628 antibody, signal transducing adaptor molecule 2 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, signal transducing adaptor molecule 2 S homeolog antibody, STAM2 antibody, Stam2 antibody, stam2.S antibody, stam2 antibody
- Background
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Description: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).
Gene: STAM2
- Molecular Weight
- 58kDa
- Gene ID
- 10254
- UniProt
- O75886
- Pathways
- EGFR Signaling Pathway, EGFR Downregulation
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