SOX9 antibody

Catalog No. ABIN6265242

Product Details anti-SOX9 Antibody

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: SOX9 Antibody detects endogenous levels of total SOX9

Cross-Reactivity: Human, Mouse (Murine)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SOX9

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500 ip 1/200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Alternative Name: SOX9 (SOX9 Products)

Synonyms: CMD1 antibody, CMPD1 antibody, SRA1 antibody, LOC100227849 antibody, 2010306G03Rik antibody, AV220920 antibody, mKIAA4243 antibody, SOX-9 antibody, cmd1 antibody, cmpd1 antibody, sox-9 antibody, sox9 antibody, sox9-a antibody, sox9-b antibody, sox9b antibody, sra1 antibody, SRY-box 9 antibody, transcription factor SOX-9 antibody, SRY (sex determining region Y)-box 9 antibody, SRY box 9 antibody, SRY-box 9 L homeolog antibody, SOX9 antibody, LOC100227849 antibody, Sox9 antibody, sox9.L antibody

Background:

Description: Transcriptional regulator (PubMed:24038782). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity). Plays a role in chondrocyte differentiation (By similarity). Important for normal skeletal development (PubMed:24038782).

Gene: SOX9

Molecular Weight: 56kDa

Gene ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development