SMPD2 antibody (Internal Region)

Catalog No. ABIN6265192

Product Details anti-SMPD2 Antibody

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: SMPD2 Antibody detects endogenous levels of total SMPD2.

Predicted Reactivity: Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SMPD2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SMPD2

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Alternative Name: SMPD2 (SMPD2 Products)

Synonyms: SMPD2 antibody, NSMase antibody, isc1 antibody, nsmase antibody, nsmase1 antibody, AW108287 antibody, nSMase antibody, nSMase1 antibody, ISC1 antibody, NSMASE antibody, NSMASE1 antibody, sphingomyelin phosphodiesterase 2 antibody, sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase) antibody, sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) antibody, sphingomyelin phosphodiesterase 2, neutral antibody, SMPD2 antibody, smpd2a antibody, smpd2 antibody, Smpd2 antibody

Background:

Description: Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.

Gene: SMPD2

Molecular Weight: 48kDa

Gene ID: 6610

UniProt: O60906

Pathways: Neurotrophin Signaling Pathway