SMC3 antibody (C-Term)
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- Target See all SMC3 Antibodies
- SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMC3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Bamacan Antibody detects endogenous levels of total Bamacan.
- Predicted Reactivity
- Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Bamacan, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product SMC3 Primary Antibody
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- Application Notes
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))
- Alternative Name
- SMC3 (SMC3 Products)
- Background
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Description: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Gene: SMC3
- Molecular Weight
- 142kDa
- Gene ID
- 9126
- UniProt
- Q9UQE7
- Pathways
- Stem Cell Maintenance
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