RUNX2 antibody (Internal Region)
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- Target See all RUNX2 Antibodies
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RUNX2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- RUNX2 Antibody detects endogenous levels of total RUNX2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RUNX2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product RUNX2 Primary Antibody
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anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibodyRUNX2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibodyRUNX2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibodyRUNX2 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibodyRUNX2 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reactivity: Human, Rat WB, IF, IHC (p), EIA Host: Mouse Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibodyRUNX2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB15321 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reactivity: Human WB, ELISA, IHC, IF, IHC (p) Host: Mouse Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) antibodyRUNX2 Reactivity: Human WB, IP Host: Rabbit Monoclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 Reactivity: Human WB, IF, IHC (p), EIA Host: Mouse Monoclonal 1D2 unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Alternative Name
- RUNX2 (RUNX2 Products)
- Background
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Description: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed:28505335, PubMed:28738062, PubMed:28703881). Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
Gene: RUNX2
- Molecular Weight
- 56 kDa
- Gene ID
- 860
- UniProt
- Q13950
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