ROR2 antibody (Internal Region)
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- Target See all ROR2 Antibodies
- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ROR2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- ROR2 Antibody detects endogenous levels of total ROR2.
- Predicted Reactivity
- Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ROR2, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ROR2 Primary Antibody
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- Application Notes
- WB 1:1000-3000, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
- Alternative Name
- ROR2 (ROR2 Products)
- Background
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Description: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443).
Gene: ROR2
- Molecular Weight
- 105kDa
- Gene ID
- 4920
- UniProt
- Q01974
- Pathways
- RTK Signaling, WNT Signaling
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