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ARHGAP24 antibody (Internal Region)

ARHGAP24 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264735
  • Target See all ARHGAP24 Antibodies
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Binding Specificity
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    Internal Region
    Reactivity
    • 27
    • 9
    • 9
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 25
    • 2
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGAP24 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    RHG24 Antibody detects endogenous levels of total RHG24.
    Predicted Reactivity
    Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RHG24, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ARHGAP24 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    Alternative Name
    ARHGAP24 (ARHGAP24 Products)
    Synonyms
    FILGAP antibody, RC-GAP72 antibody, RCGAP72 antibody, p73 antibody, p73RhoGAP antibody, 0610025G21Rik antibody, si:ch211-65i12.2 antibody, Rho GTPase activating protein 24 antibody, ARHGAP24 antibody, Arhgap24 antibody, arhgap24 antibody
    Background

    Description: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

    Gene: ARHGAP24

    Molecular Weight
    84 kDa
    Gene ID
    83478
    UniProt
    Q8N264
    Pathways
    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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