Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RFX3 antibody (C-Term)

RFX3 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264716
  • Target See all RFX3 Antibodies
    RFX3 (Regulatory Factor X 3 (RFX3))
    Binding Specificity
    • 10
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 39
    • 14
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Mouse
    Host
    • 36
    • 3
    Rabbit
    Clonality
    • 38
    • 1
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RFX3 antibody is un-conjugated
    Application
    • 27
    • 19
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    RFX3 Antibody detects endogenous levels of total RFX3.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RFX3, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    RFX3 (Regulatory Factor X 3 (RFX3))
    Alternative Name
    RFX3 (RFX3 Products)
    Synonyms
    ba32f11.1 antibody, C230093O12Rik antibody, MRFX3 antibody, zgc:153245 antibody, regulatory factor X3 antibody, regulatory factor X, 3 (influences HLA class II expression) antibody, Rfx3 antibody, rfx3 antibody, RFX3 antibody
    Background

    Description: Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5) (By similarity). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes (PubMed:20148032). Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells (PubMed:12411430).

    Gene: RFX3

    Molecular Weight
    84kDa
    Gene ID
    5991
    UniProt
    P48380
You are here:
Support