Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RCC1 antibody (N-Term)

RCC1 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264679
  • Target See all RCC1 Antibodies
    RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
    Binding Specificity
    • 22
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 68
    • 21
    • 20
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 58
    • 8
    • 2
    Rabbit
    Clonality
    • 61
    • 7
    Polyclonal
    Conjugate
    • 33
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RCC1 antibody is un-conjugated
    Application
    • 43
    • 26
    • 26
    • 14
    • 10
    • 9
    • 8
    • 7
    • 6
    • 2
    • 1
    Western Blotting (WB), ELISA
    Specificity
    RCC1 Antibody detects endogenous levels of total RCC1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RCC1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RCC1 Primary Antibody
  • Application Notes
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
    Alternative Name
    RCC1 (RCC1 Products)
    Synonyms
    Chc1 antibody, zgc:65796 antibody, zgc:77114 antibody, wu:fj77f08 antibody, rcc1 antibody, chc1-a antibody, BJ1 antibody, CG10480 antibody, CG18640 (Bj1) antibody, Dmel\\CG10480 antibody, RCC1 antibody, RanGEF antibody, Rcc1 antibody, dRCC1 antibody, inxs antibody, sdt antibody, xrcc1 antibody, chc1-b antibody, MGC115703 antibody, MGC132085 antibody, CHC1 antibody, RCC1-I antibody, SNHG3-RCC1 antibody, 4931417M11Rik antibody, AI326872 antibody, regulator of chromosome condensation 1 antibody, regulator of chromosome condensation 1 L homeolog antibody, Regulator of chromosome condensation 1 antibody, N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted antibody, regulator of chromosome condensation 1 S homeolog antibody, rcc1 antibody, RCC1 antibody, rcc1.L antibody, Rcc1 antibody, rcc1.S antibody
    Background

    Description: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).

    Gene: RCC1

    Molecular Weight
    ?45 kDa
    Gene ID
    1104
    UniProt
    P18754
    Pathways
    Chromatin Binding, Protein targeting to Nucleus
You are here:
Support