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RANBP1 antibody (N-Term)

RANBP1 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6264631
  • Target See all RANBP1 Antibodies
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    Binding Specificity
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 46
    • 20
    • 17
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 45
    • 1
    Rabbit
    Clonality
    • 46
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RANBP1 antibody is un-conjugated
    Application
    • 30
    • 14
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    RanBP1 Antibody detects endogenous levels of total RanBP1.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RanBP1, corresponding to a region within N-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product RANBP1 Primary Antibody
  • Application Notes
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    RANBP1 (RAN Binding Protein 1 (RANBP1))
    Alternative Name
    RANBP1 (RANBP1 Products)
    Synonyms
    MGC64314 antibody, zeh1094 antibody, zgc:85649 antibody, hm:zeh1094 antibody, wu:fa96a09 antibody, wu:fj39g07 antibody, HTF9A antibody, Htf9a antibody, RAN binding protein 1 S homeolog antibody, RAN binding protein 1 L homeolog antibody, ran binding protein 1 antibody, RAN binding protein 1 antibody, ran-specific GTPase-activating protein pseudogene antibody, ranbp1.S antibody, ranbp1.L antibody, PVX_090070 antibody, GL50803_16969 antibody, LOC100343953 antibody, ranbp1 antibody, RANBP1 antibody, Ranbp1 antibody
    Background

    Description: Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed:20485264). Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN (PubMed:17671426). Does not increase the RAN GTPase activity by itself, but increases GTP hydrolysis mediated by RANGAP1 (PubMed:7882974). Inhibits RCC1-dependent exchange of RAN-bound GDP by GTP (PubMed:7882974, PubMed:7616957).

    Gene: RANBP1

    Molecular Weight
    23 kDa
    Gene ID
    5902
    UniProt
    P43487
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