PSRC1 antibody (Internal Region)

Catalog No. ABIN6264498

Product Details anti-PSRC1 Antibody

Target: PSRC1 (proline/serine-Rich Coiled-Coil 1 (PSRC1))

Binding Specificity: Internal Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSRC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PSRC1 Antibody detects endogenous levels of total PSRC1.

Predicted Reactivity: Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSRC1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PSRC1

Target: PSRC1 (proline/serine-Rich Coiled-Coil 1 (PSRC1))

Alternative Name: PSRC1 (PSRC1 Products)

Synonyms: DDA3 antibody, FP3214 antibody, 5430413I02Rik antibody, AL033312 antibody, Dda3 antibody, proline and serine rich coiled-coil 1 antibody, proline/serine-rich coiled-coil 1 antibody, PSRC1 antibody, Psrc1 antibody

Background:

Description: Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.

Gene: PSRC1

Molecular Weight: 38kDa

Gene ID: 84722

UniProt: Q6PGN9