PRKCDBP antibody (Internal Region)

Catalog No. ABIN6264426

Product Details anti-PRKCDBP Antibody

Target: PRKCDBP (Protein Kinase C, delta Binding Protein (PRKCDBP))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKCDBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PRKCDBP Antibody detects endogenous levels of total PRKCDBP.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PRKCDBP, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PRKCDBP

Target: PRKCDBP (Protein Kinase C, delta Binding Protein (PRKCDBP))

Alternative Name: CAVIN3 (PRKCDBP Products)

Synonyms: PRKCDBP antibody, CAVIN3 antibody, HSRBC antibody, SRBC antibody, cavin-3 antibody, 3110015B12Rik antibody, 6330514M23Rik antibody, DIG-2 antibody, Srbc antibody, caveolae associated protein 3 antibody, caveolae associated 3 antibody, CAVIN3 antibody, Cavin3 antibody

Background:

Description: Regulates the traffic and/or budding of caveolae (PubMed:19262564). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity).

Gene: CAVIN3

Molecular Weight: 35-40 kDa

Gene ID: 112464

UniProt: Q969G5