Peroxiredoxin 6 antibody (Internal Region)

Catalog No. ABIN6264413

Product Details anti-Peroxiredoxin 6 Antibody

Target: Peroxiredoxin 6 (PRDX6)

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Peroxiredoxin 6 Antibody detects endogenous levels of total Peroxiredoxin 6.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Peroxiredoxin 6, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Peroxiredoxin 6

Target: Peroxiredoxin 6 (PRDX6)

Alternative Name: PRDX6 (PRDX6 Products)

Synonyms: 1-Cys antibody, AOP2 antibody, NSGPx antibody, PRX antibody, aiPLA2 antibody, p29 antibody, 1-cysPrx antibody, 9430088D19Rik antibody, AA690119 antibody, Aop2 antibody, Aop2-rs3 antibody, Brp-12 antibody, CC26 antibody, CP-3 antibody, GPx antibody, Ltw-4 antibody, Ltw4 antibody, Lvtw-4 antibody, NSGP antibody, ORF06 antibody, Prdx5 antibody, Prdx6-rs3 antibody, mKIAA0106 antibody, zgc:73360 antibody, aop2 antibody, prx-6 antibody, prx6 antibody, prdx6 antibody, PHGPX antibody, peroxiredoxin 6 antibody, peroxiredoxin 6 S homeolog antibody, peroxiredoxin 6 L homeolog antibody, PRDX6 antibody, Prdx6 antibody, prdx6 antibody, prdx6.S antibody, prdx6.L antibody

Background:

Description: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic  pH and to oxidized phospholipds at cytosolic  pH . Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.

Gene: PRDX6

Molecular Weight: 25kDa

Gene ID: 9588

UniProt: P30041